Boron determination in serum and plasma of rats administered boron citrate
نویسندگان
چکیده
Bor, hayvan ve insan biyolojisi için çok önemli olan dinamik bir eser elementtir. Bor sitrat, borun metabolizmaya alımındaki en yaygın formlardan biridir. Bu çalışmada oral olarak bor sitrat uygulanan ratların hem plazmalarında de serumlarında ICP-MS yöntemi ile miktarı tayin edilmiş 20 mg/kg ratlardan farklı zamanlarda alınan serum plazma numunelerindeki konsantrasyonları edilerek zamana göre değişim grafiği incelenmiştir. ugulandıkdan sonra 0,25. saatte seviyesinin maksimuma ulaştığı, 48. saatten normal seviyesine indiği görülmüştür. çalışmanın analizleri farmakokinetik özellikleri açısından temel teşkil edeceğini düşünmekteyiz.
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ژورنال
عنوان ژورنال: Bor dergisi
سال: 2022
ISSN: ['2149-9020', '2667-8438']
DOI: https://doi.org/10.30728/boron.1078402